By Kyle J. Norton
Endometriosis is a medical condition caused by the tissue of the endometrium that grows outside the uterus, leading to severe abnormal pain.
Some researchers suggested the cause of endometriosis is a result of a layer of endometriosis lining on the inside of the uterus is expelled, instead, some of the endometriosis tissues grow somewhere in the body in the last stage menstrual cycle (menstruation).
a) About 20% of reproductive age women with endometriosis present but without symptoms.
b) About 55% of women who have developed the new onset of severe menstrual cramps.
c) About 25% of women with sub-fertility (less fertile than a normal couple)
Endometriosis can vary in appearance. It may be clear or white, reddish, brown or blue-black, and cysts. The condition can be classified according to the stage of severity:
* Minimal stage:
The top surface, few in number. Commonly they are found in the inside wall of uterus, ligaments, and ovary.
* Mild stage:
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage.
* Moderate stage:
Many implants, endometrial cysts present, affecting ovary function, causing scar tissues and adhesion is also present.
* Severe stage:
Intensive peritoneal implants, large endometromas present and dense adhesion.
Each woman experiences differently to endometriosis. Some women may have extensive endometrial tissues in their body but feel little or no pain, while other women may only be in the early stage of endometriosis but have excessive pain.
With an aim to find a potential ingredient for the treatment of endometriosis-associated pelvic pain, researchers evaluated the antioxidant activity of a preparation containing N-acetyl cysteine, alpha lipoic acid, and bromelain.
The multicenter, open-label, non-comparative clinical trial included a sample of 398 patients with a mean age of 34.6 ± 7.2 years with endometriosis-associated pelvic pain.
According to the results of a combination of N-acetyl cysteine, alpha lipoic acid and bromelain treatment after 6 months, in comparison of 92.7% of the patients with pain intensity > 4 on the visual analogue scale (VAS) at the baseline, the percentage was decreased to 87.2% (p = 0.074) at 3 months of treatment.
Dr. Lete I, the lead scientist said at the final report, “Women with endometriosis who wish to become pregnant and are treated with a preparation containing N-acetyl cysteine, alpha lipoic acid and bromelain experienced a significant improvement in endometriosis-associated pelvic pain and required lower intake of rescue analgesics”.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(2) Effectiveness of an antioxidant preparation with N-acetyl cysteine, alpha lipoic acid and bromelain in the treatment of endometriosis-associated pelvic pain: LEAP study by Lete I1, Mendoza N2, de la Viuda E3, Carmona F. (PubMed)